Most Accessed Articles: BMC Medical Genomicshttps://bmcmedgenomics.biomedcentral.comMost Accessed Articles: BMC Medical GenomicsIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseaseshttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/1755-8794-2-2The production of peroxide and superoxide is an inevitable consequence of aerobic metabolism, and while these particular 'reactive oxygen species' (ROSs) can exhibit a number of biological effects, they are no...ReviewThu, 08 Jan 2009 00:00:00 GMThttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/1755-8794-2-2Douglas B Kell2009-01-08T00:00:00ZMitochondrial proteomics of nasopharyngeal carcinoma metastasishttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/1755-8794-5-62Mitochondrial proteomic alterations of nasopharyngeal carcinoma metastasis remain unknown. Our purpose is to screen mitochondrial proteins for the elucidation of the molecular mechanisms of nasopharyngeal carc...Research articleThu, 06 Dec 2012 00:00:00 GMThttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/1755-8794-5-62Jianping Liu, Xianquan Zhan, Maoyu Li, Guoqing Li, Pengfei Zhang, Zhefeng Xiao, Meiying Shao, Fang Peng, Rong Hu and Zhuchu Chen2012-12-06T00:00:00ZClinical features and molecular genetic investigation of infantile-onset ascending hereditary spastic paralysis (IAHSP) in two Chinese siblings caused by a novel splice site ALS2 variationhttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-024-01805-xALS2-related disorder involves retrograde degeneration of the upper motor neurons of the pyramidal tracts, among which autosomal recessive Infantile-onset ascending hereditary spastic paralysis (IAHSP) is a rare...ResearchWed, 31 Jan 2024 00:00:00 GMThttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-024-01805-xQiang Zhang, Qi Yang, Jingsi Luo, Xunzhao Zhou, Shang Yi, Shuyin Tan and Zailong Qin2024-01-31T00:00:00ZLoss of heterozygosity: what is it good for?https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-015-0123-zLoss of heterozygosity (LOH) is a common genetic event in cancer development, and is known to be involved in the somatic loss of wild-type alleles in many inherited cancer syndromes. The wider involvement of L...Research articleSat, 01 Aug 2015 00:00:00 GMThttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-015-0123-zGeorgina L. Ryland, Maria A. Doyle, David Goode, Samantha E. Boyle, David Y.H. Choong, Simone M. Rowley, Jason Li, David DL Bowtell, Richard W. Tothill, Ian G. Campbell and Kylie L. Gorringe2015-08-01T00:00:00ZFrom big data analysis to personalized medicine for all: challenges and opportunitieshttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-015-0108-yRecent advances in high-throughput technologies have led to the emergence of systems biology as a holistic science to achieve more precise modeling of complex diseases. Many predict the emergence of personaliz...ReviewSat, 27 Jun 2015 00:00:00 GMThttps://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-015-0108-yAkram Alyass, Michelle Turcotte and David Meyre2015-06-27T00:00:00Z