The following steps can be done either directly to the system or in a virtualenv.

1. Install dependencies:
   pip install -r requirements.txt

2. Copy txircd-example.yaml to txircd.yaml, and edit the configuration. Do the same for included files in the conf/ directory.

3. Allow txircd to daemonize:
   twistd txircd
   or run it in the foreground:
   twistd -n txircd
   (If you're running in a virtualenv, start txircd with the twistd in your virtualenv.)